Vaccinia Virus Replication and Cytopathic Effect in Cultures of Phytohemagglutinin-treated Human Peripheral Blood Leukocytes
نویسندگان
چکیده
منابع مشابه
Effect of famotidine on radiation induced apoptosis in human peripheral blood leukocytes
ABSTRACTBackground: Radioprotective effects of famotidine, an antagonist of H2 receptor clinically used for peptic ulcer treatment, was previously shown on radiation-induced micronuclei and chromosomal aberration in human peripheral blood lymphocytes and mouse bone marrow cells. This study was conducted to investigate radioprotective property of famotidine against radiation induced apoptosis i...
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The genotoxic effect of ozone was studied in human leukocytes in vitro, using the single cell gel electrophoresis (SCGE) assay. Cell treatment for 1 h at 37 degrees C with 0.9-5.3 mM O(3) resulted in a dose-dependent increase of DNA damage, comparable to that induced by 4-40 mM of H(2)O(2), used as a positive control. This effect of ozone was reversed by post-treatment incubation of the cells f...
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We have confirmed that phytohemagglutinin (PHA) rapidly enhances the uptake of potassium (K+) by human blood lymphocytes. PHA, however, did not produce an increase in lymphocyte K+ concentration. The apparent steady-state of cell K+ concentration despite the marked increase in uptake of 42K+ could be explained by either an increase in K+-K+ exchange or an increase in concentrative (active) K+ a...
متن کاملeffect of famotidine on radiation induced apoptosis in human peripheral blood leukocytes
abstractbackground: radioprotective effects of famotidine, an antagonist of h2 receptor clinically used for peptic ulcer treatment, was previously shown on radiation-induced micronuclei and chromosomal aberration in human peripheral blood lymphocytes and mouse bone marrow cells. this study was conducted to investigate radioprotective property of famotidine against radiation induced apoptosis in...
متن کاملPhytohemagglutinin: an initiator of mitosis in cultures of normal human leukocytes.
ferentiation, in short-term tissue culture, of both normal and leukemic human leukocytes obtained from peripheral blood. In the course of this study, considerable mitotic activity was observed in the cultures of normal leukocytes as well as in the cultures of leukemic “blasts.― The dividing cells in the normal cultures were tentatively identified as monocytes and large lymphocytes which had...
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ژورنال
عنوان ژورنال: Journal of Virology
سال: 1968
ISSN: 0022-538X,1098-5514
DOI: 10.1128/jvi.2.8.787-792.1968